Vetri Bladder Canine features a combination of phytoestrogens that work together to support normal bladder function and control in spayed and senior dogs. These tasty chews contain soy protein extract, a source of isoflavones, which are plant-based hormones that help maintain normal bladder muscle tone lost from spaying or aging. Red Clover Flower Powder is considered to be one of the richest sources of isoflavones available. The estrogen-like effect of red clover isoflavones may attach to estrogen receptors throughout the body to support bladder control.